Isotretinoin

Isotretinoin is a clinical-grade ingredient used to treat a variety of skin disorders. It can be formulated for both external and internal skin disorders. Topical isotretinoin is typically used for mild to moderate acne, while oral isotretinoin is reserved for severe, nodular acne and certain skin conditions like rosacea. 

Also known by its brand names Accutane and Roaccutane, is a medication commonly used to treat severe acne. It targets the sebaceous glands in the skin, reducing oil production and inflammation. 

While isotretinoin is primarily used for acne, studies have shown that it can also effectively treat rosacea, particularly in unsuccessful other treatments.

What is Isotretinoin?

Isotretinoin is a retinoid derived from vitamin A. One of its main benefits is its ability to target the condition's underlying causes. It works by decreasing the size and activity of the sebaceous glands, which can help reduce inflammation and redness associated with rosacea. Additionally, isotretinoin has been shown to have anti-inflammatory properties, further aiding in improving symptoms.

Reducing inflammation helps regulate the sebaceous glands. Less inflammation helps unclog pores, reduces the formation of acne lesions, and improves the skin's overall appearance.

Which conditions can Isotretinoin be prescribed for?

  • Rosacea

  • Acne

  • Scarring, lesions


Rosacea is a skin condition that causes redness, bumps and pimples.  Studies have shown that isotretinoin can help reduce inflammation, redness, and breakouts associated with rosacea, making it a valuable treatment option for individuals with this condition. Isotretinoin can improve the appearance of rosacea because it reduces inflammation and redness.

What are the side effects of Isotretinoin?

Isotretinoin is known to have potential side effects, some of which can be serious. While the mild side effects can include dry skin and irritation, the more severe side effects may include increased cholesterol levels, liver or kidney damage, and psychiatric symptoms. Isotretinoin is not recommended for use during pregnancy, as it can cause severe congenital disabilities. 

Isotretinoin can also cause the skin to become very sensitive to light; this is called photosensitivity. This means it is very important to use sunscreen to protect the skin from further damage. 

The effects of Isotretinoin can seem intense, but this can be a life-changing option for those with severe skin disorders.


How to add Isotretinoin to your routine

Isotretinoin is a powerful medication and should only be taken under the supervision of a healthcare provider, usually a dermatologist.

Isotretinoin is available in oral form and is typically taken once or twice daily for a period of 16 to 20 weeks. The dosage and duration of treatment will vary depending on the severity of the acne and individual response to the medication. 

Topical isotretinoin is a form of the medication that is applied directly to the skin in the form of a cream, gel, or lotion. It is typically prescribed for mild to moderate forms of acne. Topical isotretinoin works by unclogging pores, reducing inflammation, and inhibiting the growth of acne-causing bacteria on the skin's surface. It is generally well-tolerated and may have fewer systemic side effects compared to oral isotretinoin.

Both forms of isotretinoin can be effective in treating acne and certain skin conditions, but the choice between topical and oral isotretinoin will depend on the severity of the condition, the individual's medical history, and the preference of the healthcare provider. It is important to work closely with a dermatologist to determine the most appropriate treatment option for your specific needs.

If you are struggling with rosacea or serious acne and have not found relief with other treatments, isotretinoin may be worth discussing with your dermatologist to see if it is the right choice.

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